Polygenic Risk Scores Show Variability in Heart Disease Predictions
New research highlights variability in polygenic risk scores for heart disease, revealing inconsistencies in individual risk predictions that may impact clinical decisions.
Category: Cardiovascular Genetics
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Mitochondrial Function Remains Suppressed in Heart After COVID
Researchers found that while mitochondrial function recovered in the lungs, function did not recover in the heart and other organs, leading to long-term damage and a possible explanation for the detrimental effects of “long COVID.”
Unveiling the Prevalence of Bicuspid Aortic Valve and Aortic Dilation Among Family Members
A comprehensive meta-analysis reveals the prevalence of bicuspid aortic valve (BAV) and aortic dilation among relatives of individuals with BAV. The findings emphasize the importance of screening programs to identify high-risk cohorts and discuss the uncertainties surrounding clinical implications.
Read MoreThe Intricate Journey of Diagnosing Heart Failure with Reduced Ejection Fraction
The Enigma of Diagnosis Heart failure with reduced ejection fraction (HFrEF) presents a complex diagnostic challenge. The symptoms that bring a patient to the clinic are varied and often point to multiple possible diagnoses....
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Unveiling the Complexity of Hypertrophic Cardiomyopathy
A recent study conducted at the Lahey HCM Center challenges the prevailing notion that hypertrophic cardiomyopathy (HCM) is solely an inherited disease. This in-depth analysis of 304 families reveals surprising findings that shed light on the complexity of HCM and its implications for patients and their families.
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Unveiling the Hidden Links: Pregnancy Complications as Predictors of Future Cardiovascular Disease
The impact of pregnancy complications on women’s long-term health is garnering increasing attention. Researchers have found that conditions like hyperemesis and preeclampsia are associated with a higher risk of cardiovascular disease later in life. Unravel the complex links between pregnancy complications and cardiovascular health, and explore the potential for early interventions to reduce long-term risks.
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Link Between Opioid Hormone and Cognitive Impairment: Insights from Cardiovascular Risk Marker
A recent study investigates the connection between the opioid hormone pro-enkephalin A (PENK-A) and cognitive impairment. The findings reveal that high and low levels of PENK-A are associated with decreased odds of future cognitive impairment in specific subgroups. Further research is needed to understand the underlying biology and the observed differences by sex.
Read MoreUnveiling the Complexities of Exercise Tolerance in Patients with Pulmonary Arterial Hypertension
Introduction Pulmonary arterial hypertension (PAH) is a debilitating condition characterized by high blood pressure in the pulmonary arteries, which connect the heart to the lungs. This chronic and progressive disease...
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The Link Between Neonatal Depression and Mortality in Critical Congenital Heart Disease: Insights from National Data
A new study using US national vital statistics data sheds light on the link between neonatal depression (low Apgar scores) and 1-year mortality in critical congenital heart disease (CCHD). The study identifies risk factors for neonatal depression and highlights the importance of using Apgar scores as a prognostic indicator in CCHD. These findings have implications for prenatal management and improving CCHD mortality rates.
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Unraveling the Complexities of Fetal Congenitally Corrected Transposition of the Great Arteries: Predictors of Clinical Outcomes Explored
A comprehensive multicenter study examines fetal congenitally corrected transposition of the great arteries (ccTGA) to identify predictors of clinical outcomes. The study highlights associated cardiac lesions, arrhythmias, and key risk factors, providing valuable insights for prenatal counseling, follow-up, and delivery planning in ccTGA cases.
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Personalized Precision Medicine: ESC Guidelines Aid Risk Stratification for Non-ST-Elevation ACS Patients Undergoing PCI
The 2020 ESC guidelines offer a valuable tool for clinicians to determine thrombotic risk categories in non-ST-elevation ACS patients undergoing PCI. High-risk patients, as identified by the guidelines, are found to have a significantly increased bleeding risk. These findings pave the way for personalized precision medicine in managing this patient population.
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